ZydermŪ
& ZyplastŪ
Introduced 18 years ago, Zyderm® and Zyplast®
injectable collagen implants have set the standard
in filler materials for smoothing facial lines,
wrinkles and scars and in providing lip border
definition. Treatments supplement the skin’s
natural collagen, require minimal procedure time,
and provide immediate results. Today, more than
one million people worldwide have been treated
with Zyderm® or Zyplast® collagen implants.
Zyderm and Zyplast implants are composed of highly
purified bovine dermal collagen that is dispersed
in phosphate buffered physiological saline containing
0.3% lidocaine.
Zyderm and Zyplast implants are indicated for
the correction of contour deformities of the dermis
in non-weight bearing areas. These implants have
been employed successfully in many areas of the
body to correct distensible acne scars; atrophy
from disease or trauma; glabellar frown lines;
nasolabial folds; rhinoplasty, skin graft or other
surgically-induced irregularities; and other soft
tissue defects.
Zyderm and Zyplast implants are produced in
various formulations, which are appropriate for
different facial areas and conditions.
Facial Applications
Zyderm 1 implant is used to treat fine lines,
wrinkles, shallow scars and thin-skinned areas.
Zyderm 2 implant is used to treat moderate lines,
wrinkles and scars.
Zyplast implant is used to treat pronounced
lines and wrinkles, scars, and thicker-skinned
areas.
Key Benefits
Patients experience immediate, visible results.
Treatment with Zyderm or Zyplast implants is an
easy and effective way to smooth lines, wrinkles,
scars, and to define the lip border. An immediate,
visible difference in the patient's appearance
may be achieved in one treatment session.
Ease of Treatment
Four weeks prior to the procedure, Collagen
Test Implant is administered intradermally into
the volar forearm to determine if a patient has
a sensitivity to the implants. Ninety-seven percent
(97%) of men and women tested can be treated with
Zyderm and Zyplast implants.
If a patient is eligible to receive treatment,
Zyderm and Zyplast implants are implanted intradermally
through a fine gauge needle into the appropriate
facial planes needed for correction. Treatment
with Zyderm and Zyplast implants consists of a
simple in-office procedure that can be completed
quickly and conveniently, even during a lunch
hour. Most patients return to their normal routine
immediately following the procedure.
An ongoing series of customized treatments can
preserve the look that is desired. These treatments
are as easy and convenient as the first one.
Proven Results
Zyderm® and Zyplast® implants, introduced
in the early 1980's, remain the most widely used,
safe, and effective choices for smoothing lines,
wrinkles, scars, and for defining the lip border.
More than1 million treatments in over 40 countries
have been administered with Zyderm and Zyplast
implants.
Rigorous clinical trials to determine the safety
and efficacy of Zyderm and Zyplast collagen implants
were conducted from 1976 to 1981. This data was
submitted to the Food and Drug Administration
and Zyderm and Zyplast implants were cleared for
marketing in 1981 and 1985 respectively. No other
injectable collagen implants currently on the
market have undergone such extensive study.
Usage Information
More than one million treatments in over 40
countries have been administered with Zyderm and
Zyplast implants.
Dermatologists, plastic surgeons, facial plastic
surgeons, and aesthetic doctors use Zyderm and
Zyplast implants in their practices
Nurses who are trained as collagen specialists
administer Zyderm and Zyplast implant treatments
under the supervision and guidance of a doctor
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